The other player in the space is Filemaker Pro - a fair bit nicer to work with than Access, although still fairly horrible from an internals point of view (I think they've moved to using proper SQL and everything since I last used it though).
I used to work for a web developer who worked on a well known campground company's site. We had a process that built static html pages out of an old Filemaker database and then synced them to a cluster of Windows web servers. That process has been in place since 2000 and there's no rush to change it because, frankly, it works pretty well.
I believe it started that way because our original developer didn't know anything else.
